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The aggressive titration tail in the 12 mg arm of the Phase 2 trial was strongly associated with higher rates of transient gastrointestinal adverse events, which is why researchers generally favor slower escalation when tolerability is prioritized
Diabetes 54 , 10561063 (2005)
Although in most cases, they are quite successful in producing substantial weight loss, many have regained weight after the medication was discontinued
Other reta boosters also flag its alleged ability to reduce cravings for drugs and alcohol
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