Clear human evidence is lacking
Growth and Development In newborns, basal IGF-1 levels are low, but as humans develop, the GH feedback loop and the regulation of IGF-1 become more pronounced.7 Circulating IGF-1 stimulates growth in all cells, from skeletal muscle and bone to organ tissue and vessel linings
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Despite there being no research directly on the copper uglies phenomenon, it may be due to the peptides effects on collagen