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It is extensively present in all eukaryotes and is particularly concentrated in the liver

The governing idea is that each tissue in the body maintains its own population of endogenous short peptides that help regulate cell division, differentiation, and gene expression within that tissue, and that supplying the corresponding synthetic peptide can, in theory, help restore normal function to an aged or stressed tissue

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A FOXO4 Inhibitory Peptide Limits Chemotoxicity in Mice