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Muscle and bone loss is a growing concern
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However, GLP-1 receptor agonists like semaglutide and liraglutide may delay gastric emptying, which could theoretically affect the absorption of oral medications including levothyroxine
At steady state, average blood levels are higher and more stable than after the first dose, which often translates into smoother appetite and glucose effectsand sometimes more noticeable GI side effects during dose increases
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