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To assess the extent of apoptosis, we performed TUNEL staining experiments

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Overall, dental pulp stem cell therapy demonstrated therapeutic efficacy in improving clinical outcomes in the treatment of periodontitis, enhancing both soft and hard tissue parametersincluding attachment loss, periodontal probing depth, and bone defect depthoutcomes that have not been previously reported in the literature

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Maturation skews macrophage polarization from M1 to M2 (interleukin-4 [IL-4], interleukin-10 [IL-10], IL-12, Arginase 1 [Arg-1]