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This large-scale analysis suggests that OSA status may act as an effect modifier in the association between GLP-1-RA prescription and mortality. The results of this study may lead to OSA diagnosis identifying diabetes patients more likely to derive mortality benefit from GLP-1 therapythe 20% greater relative mortality reduction in patients with OSA supports considering OSA status when making GLP-1 prescribing decisions, the investigators say

Presented for research literature review only Farooqi MF et al

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Key takeaways: 27% of respondents noticed changes to their menstrual cycle since starting GLP-1 medication for weight loss Respondents with PCOS were more likely to experience cycle changes, and 43% of this group reported noticing changes to their menstrual cycle The most commonly reported cycle changes were more predictable periods, more frequent periods, and shorter periods GLP-1 medications like semaglutide (Ozempic) and tirzepatide (Mounjaro) have traditionally been used to treat diabetes

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