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It is also approved to treat moderate-to-severe binge-eating disorder in adults, although it is not approved as a weight-loss medication
Reflux can be uncomfortable, but for most people its manageable
The patients who perform best during GLP-1 therapy are usually not the ones relying on the medication alone
Investment Strategy: Biologics LOE For institutional investors, the analytical question at a biologic LOE is not how much will biosimilars capture but rather: (1) what is the net price convergence trajectory between the reference product and biosimilar competitors under real-world formulary conditions, (2) does the innovator have pre-negotiated rebate contracts that lock in formulary position for 12 to 24 months post-launch, (3) what is the IP stack on the successor asset, and (4) how far along is the clinical conversion to a reformulated or combination version that carries fresh exclusivity
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