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In common parlance, everybody calls them GLP-1s because they mimic a natural hormone called GLP-1
Davidson DG, Eastham WN
In clinical practice, SGLT2 inhibitors are often initiated first due to their oral administration and broader reimbursement, with GLP-1 receptor agonists subsequently added to address persistent hyperglycemia, excess body weight, or residual albuminuria [84,85]
Moving forward, dynamic monitoring of resistance-related pathways, integration of multiomics analyses, and implementation of immune intervention strategies will be essential to develop personalized and mechanism-guided endocrine treatment approaches
PubMed Maquart, F.X., Pickart, L., Laurent, M., Gillery, P., Monboisse, J.C., & Borel, J.P
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