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A synthetic compound called carbonyl cyanide-m-chlorophenyl hydrazone (CCCP) was found to act as a decoupler that disrupts the proton motive force of the pump, resulting in an antibiotic-potentiating effect with tetracycline against Helicobacter pylori and Klebsiella , alleviating gastrointestinal tract-associated diseases 82,83
Samples were incubated at room temperature for 1 h, vortexing intermittently, and then quenched by the addition of hydroxylamine (5 L of 5% w/v in HPLC water per sample) and incubated for 15 min at room temperature
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"Glutathione reductase deficiency in Saudi Arabia"
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