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Pharmacological Reviews, 1998
2017 Jun;64(6):673-674 Koratala A, Chamarthi G, Segal MS
It works by binding directly to the IGF-1 receptor (IGF-1R) on muscle and other tissue, activating the PI3K/Akt and MAPK signaling cascades that drive cell growth and proliferation
Visible body-composition changes usually develop over 812+ weeks when paired with nutrition, movement, and sleep optimization
Steroids decrease the production of inflammatory chemicals and reduce the sensitivity of nerve fibers to pain, generating fewer pain signals
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