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Case Presentation We present a case of colonic ischemia in a young patient who experienced significant nausea, vomiting, and abdominal pain after initiation of semaglutide

Multiple sclerosis GLP-1 receptors are expressed in the central nervous system, and some preclinical research suggests neuroprotective effects from GLP-1 receptor agonism

Nausea, vomiting, and constipation are common in the first weeks

Ingenol gel or photodynamic therapy is more suitable for flat keratoses or larger areas of sun-damaged skin

Ultra-low calorie intake: Eating fewer than 1,000 calories daily, which is easy to do accidentally when appetite is dramatically suppressed, triggers metabolic adaptation that actually slows weight loss over time