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Though the medication was originally developed as a diabetes drug, its been shown to be effective for a myriad of conditions, like polycystic ovarian syndrome and migraines

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(B-D) Traces demonstrate acute effects of Ex-4c on membrane potential when the cell was pretreated with (B) 10 M linopirdine+10 M XE991, (C) 100 nM tertiapin-Q, or (D) 200 M tolbutamide

Each of these isozymes is differentially expressed in tissues and developmental stages