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Pazienti diabetici La somministrazione di Lcarnitina in pazienti diabetici in trattamento insulinico o con ipoglicemizzanti orali, migliorando lutilizzazione del glucosio, potrebbe determinare fenomeni di ipoglicemia
Subtle toxicities (like mitochondrial stress, hepatocellular changes, or rare vascular events) may manifest only over time
Next to cytokines and cellular stress pathways, such as the unfolded protein response (UPR), alterations in the enteroendocrine system are intersections of various pathologies
Long-term HFD consumption increased hepatic IKK- glutathionylation and NF-B suppression The mechanistic investigations in our cell culture studies provided evidence suggesting that intracellular GSSG accumulation sensitizes hepatocytes to TNF cytotoxicity via the induction of IKK- glutathionylation, leading to reduced IKK- phosphorylation and subsequent NF-B suppression
The role of gut microbiota in the development of obesity and diabetes (in Eng)
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