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Human trials of IGF-1 in PD have not yet been performed, but studies in rat models of PD indicate that it protects dopaminergic neurons and improves behavior
Wagner K, Vito S, Inceoglu B, Hammock BD
Important safety considerations include risks of acute pancreatitis (seek medical attention for severe abdominal pain with or without vomiting), gallbladder disease, dehydration, and potential worsening of diabetic retinopathy with rapid improvement in glucose control
Understanding Semaglutide and GLP-1 Medications Semaglutide, sold under the names Ozempic (for type 2 diabetes) and Wegovy (for weight management), is a GLP-1 receptor agonist
Agents with direct relevance to the psoriasis-comorbidity matrix include: Semaglutide SC (Ozempic/Wegovy): The most studied agent in cardiovascular and metabolic outcomes
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