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Studies have shown that DSIP can pass the blood brain barrier (BBB) in rats, mice, dogs, and humans, making it a potential option for targeting neurological disorders, aforementioned mood disorders, and sleep disorders [11]
and globally remains limited compared to the unmet medical need
DPP-4 inhibitors: DPP-4 inhibitors work by inhibiting the activity of dipeptidyl peptidase-4 (DPP-4), which reduces the breakdown and inactivation of the incretin GLP-1 (glucagon-like peptide-1), leading to increased endogenous levels of GLP-1
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