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An important consideration: Retatrutide trials lasted 48 weeks while Tirzepatide trials extended to 72 weeks
In this context, the present work evaluated the applicability of the commercially available upper MucilAir-HF and lower EpiAlveolar human lung models to be used as in vitro systems within a NAM toolbox to identify the bioactivity (i.e., in vitro PoD derivation) and risk of materials that may reach the respiratory tract and induce lung toxicity
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doi:10.2337/dc13-2618 48
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