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[6] The story of GLP-1s in metabolic health is therefore not just about slimmer waistlines

Myth GLP-1 medications are a quick fix Myth Everyone loses weight in the same way Myth GLP-1 medications simply "turn off hunger" Myth Online programs offer the same care as medical clinics

While pharmaceutical GLP-1 receptor agonists provide potent therapeutic effects, several evidence-based lifestyle and dietary strategies may support endogenous GLP-1 secretion

Future studies should identify its active constituents, elucidate downstream effectors, and validate this mechanism in germ-free models

JAMA 2022;327:53445.ArticlePubMedPMC 56