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The inactivation of SLC7A11 due to ubiquitination also induces ferroptosis in NSCLC[89] and ovarian cancer cells[68]

Debated Unsettled Safety Issues Cancer Concerns about a possible connection between GLP-1 RAs and the development of neoplasms have spurred several investigations, especially on thyroid and pancreatic cancers due to a plausible mechanism and a large number of reports in the post-marketing phase [118, 128, 130]

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