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This tripeptide fragment of alpha-melanocyte-stimulating hormone has been studied for its potential anti-inflammatory properties, including effects on the NF-B and MAPK signaling pathways

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DOI: 10.1111/bjd.13598 MC1R Selectivity and Receptor Pharmacology Comparative receptor binding studies have confirmed MT-1s preferential activity at MC1R versus the broader receptor profile of MT-2, establishing it as the reference compound for isolated MC1R pathway research