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[9] SAM-e evidence Glutathione depletion Treatment Yasko's Protocol The Yasko protocol looks at two different pathways of the methylation cycle, which she calls the long route and the short cut

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A meta-analysis of 26 RCTs (n=3,864) found that NAC (typically 600 mg twice daily) reduced the incidence of contrast-induced nephropathy by 40% (OR 0.60, 95% CI 0.44-0.81) (Gonzales et al., BMC Med, 2007) [67]

The difference between these two antioxidants really comes down to how your body produces them