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This finding was consistent for cardiovascular mortality (HR 0.90, 95% CI from 0.50 to 1.61) and all-cause mortality (HR 0.80, 95% CI from 0.51 to 1.25)

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Patients in this borderline range should not dismiss symptoms simply because their B12 level is above the strict cutoff clinical context and additional testing matter

These studies utilized the theoretical framework that the combination of nutrients will have a greater effect than the individual nutrients