Cyclic Heptapeptide Lactam-Bridged Macrocycle -MSH Analogue Reported Pharmacology (Literature, Neutral) Reported Melanocortin receptor agonism Non-selective MC1R / MC3R / MC4R / MC5R agonist Molinoff and colleagues (Ann N Y Acad Sci 2003) reported: PT-141, a synthetic peptide analogue of alpha-MSH, is an agonist at melanocortin receptors including the MC3R and MC4R, which are expressed primarily in the central nervous system. Reported as a neutral pharmacology statement in the academic record
Abe, Y., et al., Human germline hedgehog pathway mutations predispose to fatty liver
FDA-approved for reducing visceral fat
We also dive into GLP-1 drugs, discussing their origin and their neurologic benefits, debunking the myths surrounding them, and examining their use during perimenopause and menopause
17% identified as Hispanic or Latino ethnicity