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Because cobalamin in normally absorbed from food through the gastrointestinal tract, chronic diseases that adversely affect the ability of the intestines to absorb nutrients (inflammatory bowel disease is an excellent example) can lead to cobalamin deficiency
Dig Dis Sci 54:20702083 Sikiric P, Seiwerth S, Rucman R, Turkovic B, Rokotov D, Brcic L, Sever M, Klicek R, Radic B, Drmic D, Ilic S, Kolenc D, Aralica G, Stupnisek M, Suran J, Barisic I, Dzidic S, Vrcic H, Sebecic B (2014) Stable gastric pentadecapeptide BPC 157-NO-system relation
Nutrient deficiencies No stomach for cancer
Since obesity is related to many other diseases, semaglutide helps with those as well