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Patients were included in both cohorts if they had filled a first prescription for both drug classes

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The mitochondrial protease LonP1 promotes proteasome inhibitor resistance in multiple myeloma

You can advise them to 2 : Eat bland, low-fat foods, like crackers, toast, and rice Eat foods that contain water, like soups and gelatin Avoid lying down after they eat Go outside to get some fresh air Talk to your patients about potential side effects, including nausea, and how to manage them If patients cannot tolerate an increased dose during dose escalation, consider delaying escalation for approximately 1 week

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