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(Nov.2024) Semaglutide, a GLP-1 medication, is the first weight loss medication approved to reduce the risk of cardiovascular death, heart attack and stroke in adults who have cardiovascular disease and are overweight or obese.
They help lower blood sugar by stimulating insulin release, but until now it has remained unclear how they also strengthen the mitochondria, the tiny energy-producing structures that keep -cells functioning and resilient
PMID: 14647006
In future research, more human cohort studies can be conducted to correlate TMAO levels with IBD phenotypes through multi-omics analysis
In terms of weight loss at comparable time points, tirzepatide consistently outperforms semaglutide in clinical trials
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