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The PIONEER 6 trial, a recent double-blind randomized noninferiority trial, examined cardiovascular outcomes following daily treatment with oral semaglutide or placebo in addition to standard care in 3,183 patients with type 2 diabetes aged at least 50 years with cardiovascular or chronic kidney disease (84.7 percent) or aged at least 60 years with cardiovascular risk factors only (15.3 percent)
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