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The PGD gene is located on chromosome 1p36.33 and is composed of 13 exons that generate three alternatively spliced mRNAs, each of which encode different sized protein isoforms
Clinical Trial Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice
Unknowns remain large because human trials on the combined blend do not exist
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We use the model to simulate the metabolic profiles previously observed in Down syndrome and autism and compare the model results to clinical data
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