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In the context of an aging population and its associated public health challenges, addressing obesity in older adults is particularly demanding due to barriers such as resistance to lifestyle changes
Various metabolites, such as lactate that is produced by tumour cells rely on the glycolytic pathway to reshape the homeostasis and metabolism of the microenvironment, resulting in higher lactate abundance
Clinical implications
So, it would make sense that medication that improves insulin resistance and decreases patients weight helps with HS. Obesity triggers low-grade, chronic inflammation, and that makes HS worse, adds Ife J
The general calorie frameworks are similar, but there are meaningful differences worth understanding
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