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The role of GLP-1Rs on tanycytes remains to be fully characterized, but they may be involved in transport of semaglutide into the ARH
Summary: GLP-1 receptor agonists are not specifically licensed for menopausal weight gain but may be prescribed for women meeting obesity treatment criteria (BMI 35 kg/m with comorbidities) during the menopausal transition
It is also contraindicated in patients with a history of pancreatitis or gastrointestinal issues since it increases gastrointestinal emptying time which can intensify symptoms
By supplementing with specific peptides, you may be able to nudge these systems back into balance, particularly if stress, age, or lifestyle factors have thrown them off course
DPP, dipeptidyl peptidase
