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Change in cytokine levels is not associated with rapid antidepressant response to ketamine in treatment-resistant depression

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Tricyclic antidepressants including imipramine and amitriptyline are a mainstay of treatment for a variety of chronic pain states, although not FDA-approved for this indication (Tauben & Stacey, 2021)

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Intentional lifestyle habits can also improve sleepkeeping your room cool, limiting caffeine and alcohol later in the day, winding down before bed, and/or prioritizing daily exercise can be game-changers