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This maleimidopropionic acid sometimes called the drug affinity complex (DAC), forms stable covalent linkages with free thiol groups on the surface of plasma proteins such as serum albumin[1]

Severe abdominal distension, inability to pass gas or stool, or worsening constipation may signal intestinal obstruction or ileus

Evening injections, while potentially worrying due to concerns about affecting sleep, do not seem to disrupt children's sleep patterns according to study data

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50% for vitamin C and 40% for tretinoin), without the irritation or photosensitivity that retinoids commonly cause