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A 2021 study on nalfurafine, a -opioid agonist metabolized by cytochrome P450 into an inactive form, showed significant improvement in pruritus scores without notable adverse effects at doses of 2.5 mg and 5 mg, regardless of daytime or nighttime itching (24)
Dai Z, Zhao T, Song N, Pan K, Yang Y, Zhu X, et al
"GLP-1s may offer a dual benefit for patients with chronic conditions like diabetes or obesity who are also struggling with a substance use disorder: one medication can treat both conditions at once," Al-Aly said
Strauss RG, Ciavarella D, Gilcher RO, et al
These portable sprays offer a 30-day supply and can be taken anywhere, at any time
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