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Sex-specific signaling, while potentially advantageous, complicates trial design and regulatory evaluation
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For general health benefits, a daily dosage of 500 to 1,000 mg is usually sufficient
Weight loss effects vary by indication: in adults with obesity without diabetes, weight loss of up to 21% has been observed at 72 weeks on the 15 mg dose, while patients with type 2 diabetes typically experience 5-12% weight loss
doi: 10.1016/J.JDIACOMP.2024.108834 101 VarnumAAPozziEDeebelNAEvansAEidNSadeghi-NejadHet al
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