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Describing herself as largely 'the lab rat' when she joined the diabetes team, Knudsen remembers she spent 'the first year in a cold room with three technicians to screen hundreds of thousands of compounds to see if they could wedge into the GLP-1 receptor and other targets of interest just snugly enough to stimulate insulin secretion.' To help speed up the screening process, Knudsen devised a method to test 96 candidates in one go instead of just one
Retatrutides data set is still being generated
Liver and biliary blood tests may support evaluation of gallbladder symptoms, but ultrasound or other imaging is often necessary
The symptoms of PWS are often evident in infancy and change over time
Parents of participants provided written informed consent (visit 1)
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