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5 hiPSC-derived models as tools to identify disease-associated biomarkers Disease-specific biomarkers have a crucial role in precision medicine, as they can help to identify specific characteristics that indicate the presence of progression of a particular disease, allowing clinicians to make accurate diagnoses, categorize patients into subtypes based on their biomarker signature and ultimately develop targeted interventions and treatments

The presence of MDHAR, if it is effective enough in competing with MDHA dismutation, means that DHAR, glutathione, and GR are not necessarily required to regenerate ascorbate (Fig

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2020;3:e2028117

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