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GSH repletion has been proposed as a therapeutic intervention
3.2 Amino acid metabolic reprogramming 3.2.1 The central role of the glutamate-GSH pathway in ferroptosis Ferroptosis is highly dependent on GPX4-mediated reduction of lipid peroxides, and reduced GSH serves as GPX4s substrate
As such, the current evidence demonstrates association, not proven causality
Found naturally in your cells, it plays a critical role in detoxifying harmful substances, neutralizing oxidative stress, and supporting overall cellular health
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