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Indeed, if there is a methionine deficit, homocysteine can be re-methylated to form methionine, and if there is an adequate amount of methionine, homocysteine is used to produce cysteine (161)

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This discrepancy in clinical recommendations underscores the critical need for comprehensive real-world evidence studies to elucidate the safety profile and adverse reaction patterns associated with combination therapy

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However, because it supports detoxification, it may indirectly improve overall cellular balance without acting as a hormonal treatment