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Mechanistically, an expanding body of preclinical/translational research suggests that the gut-microbiome impacts breast carcinogenesis and therapy through several interrelated pathways-chiefly in terms of its estrobolome (microbial pool of genes dedicated to estrogen metabolism), bioactive microbial metabolite synthesis, systemic/mucosal immunity modulation (influencing T-cell subsets/myeloid cell function/inflammatory cytokine networks) also together with drug pharmacokinetics/pharmacodynamics (175)
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Those are two different statements, and we keep them separate on purpose
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