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Important unresolved questions include whether BPC-157 reaches relevant central compartments under specific experimental conditions, whether observed CNS model effects depend primarily on vascular preservation, whether neurotransmitter changes are primary or secondary, and whether the brain-gut-axis hypothesis can be separated experimentally from general systemic effects
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In agreement with this finding, compound C also abolished the synergistic ameliorating effect of combination treatment with lower dose of metformin and liraglutide on the PA-induced reduction of p-eNOS protein level (Supplemental Fig
in: PubMed | Google Scholar 1 Global Drug Discovery and 2 Global Research Technologies, Novo Nordisk A/S, Mlv, Denmark, and Seattle, Washington, USA
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