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Mechanisms That May Explain Enhanced Weight Loss Reduced energy intake GLP-1 receptor activation reduces appetite and food intake through hypothalamic, hindbrain, vagal, and gastrointestinal mechanisms
Numerous other routes could allow oxidation of GSH to GSSG
P =0.05) (Figure 2B)
Body weight and food intake were measured manually each day at the time of injections
This alteration is accompanied by a metabolic change from glycolysis to a more oxidative form given by a decrease in phosphoglycerate mutase 1 (PGAM1), ALDOA, LDHA/B, and an increase in succinate dehydrogenase (SDH) A/B/C/D from the ADP-forming beta subunit of succinate-CoA ligase (SUCLA2), aconitase 2 (ACO2), PDK, and pyruvate dehydrogenase phosphatase (PDP), among others
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