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[23] Antivitamin B 12 compounds (often synthetic B 12 analogues) not only have no vitamin action, but also actively interfere with the activity of true vitamin B 12
For humans, 5-Amino-1MQ is still in the experimental stage, but anecdotal reports and early user experiences are trickling in
Patients with pancreatic insufficiency may have reduced cobalamin absorption (because pancreatic enzymes normally assist with the displacement of salivary haptocorrin binding protein by intrinsic factor), although such patients rarely become cobalamin deficient
This involves clinical checks, lab tests, and risk assessments
One limitation is its short serum half-life of approximately 2 hours
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