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Understanding both PK and PD, helps estimate the exposure levels likely to be efficacious and the exposure levels that might induce side effects in humans

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Once you know the concentration in mg/mL, a dose in mg becomes a volume in mL by simple division, and that volume becomes insulin-syringe units by multiplying by 100 (because a U-100 syringe is marked so that 1 mL = 100 units)

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Abdominal sites heal quickly and cause minimal bruising when rotated properly