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Nausea is most pronounced during dose escalation windows, particularly around weeks six to eight when doses are increasing, and typically diminishes substantially by week twelve as tolerance develops
In rare instances, this may cause small tears in the oesophageal lining (Mallory-Weiss tears) or irritation to the gastric mucosa, potentially resulting in haematemesis (vomiting blood) or melaena (dark, tarry stools indicating upper gastrointestinal bleeding)
Recent guidance highlights aspiration risk during anesthesia due to delayed gastric emptying
The fear of reporting marijuana use by patients before legalization is certainly a limitation of the study, and may have led to overestimation of the increase seen in CHS visits
physicians see it as a slow erosion of medical professionalism
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