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Out-of-competition testing targets substances that provide training advantages even when not used immediately before competition

In addition to integrating the complementary actions of two endogenous metabolically related hormones targeting glucagon-like peptide-1 and glucagon receptors (GLP-1R and GCGR), the synergistic targeting of a third G protein-coupled receptor (GPCR), namely the gastric inhibitory polypeptide receptor (GIPR), may achieve optimal control of blood glucose levels and weight loss in patients with diabetes and obesity

EMA will communicate further when appropriate

doi: 10.7759/cureus.17258

However, their efficiency depends on the nature of the black circles