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In people with obesity and established cardiovascular disease but without diabetes, semaglutide 2.4 mg resulted in 20% reduction in major adverse cardiovascular events [(MACE), death from cardiovascular causes, nonfatal myocardial infarction or nonfatal stroke] compared to placebo (SELECT trial) after a mean follow-up of 39.8 months this is the first trial demonstrating cardiovascular benefit for an obesity pharmacotherapy [110]
Inhibits NNMT, elevates NAD+, enhances fatty acid oxidation, reduces fat accumulation and lipotoxicity
They claim the product is for research or not for human consumption to dodge FDA jurisdiction, Holt says
Bethany Tennant, N.D., C.N.S., is a naturopathic doctor and certified nutrition specialist in Portland, Oregon
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