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In a statement to Insider, Novo Nordisk, the company that makes Wegovy and Ozempic, said that Gila monsters and the discovery of exendin-4 "did not have anything to do with our decision to develop long-acting GLP-1 receptor agonists" for obesity, because "that was based on GLP-1 biology in humans." But the company also said that "the GLP-1-like effect of exendin-4" in Gila monsters was "an important contribution to the field," as it led to the development of the very first injectable drug of its kind

For most people, the hardest stretch of a GLP-1 is the very beginning

: Injectable GLP-1 Receptor Agonists Oral GLP-1 Weight-Loss Drugs Combination GLP-1/GIP Therapies : Obesity Treatment (BMI 30) Overweight Patients with Metabolic Disorders Type-2 Diabetes with Weight Management Clinical & Pharmaceutical Research : North America Europe Asia-Pacific South America Middle East & Africa : Novo Nordisk A/S Eli Lilly and Company Pfizer Inc

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This is a feature, not a failure