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This action leads to a reduction in intracellular GSH levels, resulting in increased oxidative stress, which induces apoptosis and cell cycle arrest
Early use of n-acetylcysteine with nitrate therapy in patients undergoing primary percutaneous coronary intervention for ST-segment-elevation myocardial infarction reduces myocardial infarct size (the NACIAM Trial [N-acetylcysteine in Acute Myocardial Infarction])
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