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2 In a key secondary endpoint, more than 65% of participants taking the highest dose of orforglipron achieved an A1C less than or equal to 6.5%, which is below the 3 In an additional key secondary endpoint, participants taking orforglipron lost an average of 16.0 lbs (7.9%) at the highest dose
You'd need to consume 50g+ at lunch and dinner, which is hard to tolerate on GLP-1s
Build your smaller plates around these anchors: Lean Protein (Fish, poultry, tofu, eggs, Greek yogurt) Vegetables & Fruit (Volume + micronutrients) Fiber-Rich Carbs (Berries, beans, small portions of whole grains) Healthy Fats (Avocado, olive oil, nuts) On very low-appetite days, a protein shake or yogurt bowl is a perfect way to hit your protein target without discomfort
In this context, GLP-1RAs have emerged as promising candidates for disease modification, owing to their pleiotropic neuroprotective effects demonstrated in preclinical and clinical studies [268, 286]
Patients should maintain consistent hydration and report dark urine, dizziness, or reduced urination to their healthcare team immediately
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