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[1] Renal Transporter Considerations Dapagliflozin is also a substrate of P-glycoprotein (P-gp) and organic anion transporter 3 (OAT3) to a minor degree
Despite higher doses, IGF-1 increases often more modest (40-70 ng/mL) reflecting reduced secretory capacity
Broader receptor activity can also lead to more systemic effects, which is why safety and side effects are often studied
Traditional DS (BPD-DS) Traditional duodenal switch has two intestinal connections
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