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Mean baseline HbA1c was 7.83% and 7.80%, and baseline BMI was broadly comparable across included trials, with mean values of approximately 33.3 kg/m 2 for semaglutide and 33.6 kg/m 2 for tirzepatide, and an overall range of approximately 31 to 36 kg/m 2
The honest reading of the literature is that response, where it has been reported in small studies, is gradual, variable between individuals, dependent on formulation, and often confounded by the presence of other actives
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